Looking for a cool plush hotel in London - 5 star hotel, 3 star prices!

What are some of the nicer hotels that you have stayed at when on business travel. Any non-chain ones that you would recommend in the larger metro areas, SF, NY, Chicago, etc?

I like to stay at W Hotels. Unfortunately The W in London doesn't open till October 2010. Which other SPG hotels are of similar standards? Le Meridien looks like it has a great loc …